Alzheimer's disease is caused by the build up of plaque, a secondary immune response, in the brain. The secondary response is invoked because the standard immune system cannot cross the blood brain barrier.
The virus that triggers the immune system is very common. More than half of all humans are infected with it. Most of the time it rests dormant in the dorsal root ganglia. When it does move around (often in younger individuals, but not always) schizophrenia can be a common diagnosis. This is often also associated with sleep disorders.
When outbreaks of this virus occur …they are usually associated with some illness or disease, occurring elsewhere in the body. Outbreaks are called cold sores or fever blisters for this reason.
In 2012, I accidentally discovered the chemical trigger for herpes outbreaks. It is related to breakdown of bodily protein to supply amino acids to quickly make immune components. This is the signal the virus relies upon to say that it is OK to leave the safety of the protective blood brain barrier.
Older individuals have less spare bodily protein remaining in their physical structure. Ramp up to fight infection takes longer. They may not produce much of a signal …because of less available protein, so the virus may remain dormant for years and years.
Eventually, increase in plaque causes the virus to move or it will become trapped within the plaque. This movement could trigger the sleep disturbances referred to in your question.
If you have actual need, there are 12 doses remaining from clinical trials. As a clinical pharmacist, I'm confident they are safe for use by the general public. The worst (or actually best) outcome is triggering an outbreak when the standard immune system is not busy elsewhere. It would stop the plaque by removing the stimulant!
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