Showing posts with label Fish. Show all posts
Showing posts with label Fish. Show all posts

Saturday, 24 February 2018

Abkhasians - the long-living peoples (110-130 yrs) - Goat cheese, yogurt, wine, lots of garlic, mashed lima beans, NO MEAT STOCK

The Abkhasians had a way of life that is out of reach for modern man, or so it seems! One of the arguments that is often used to promote modern medical technology (vaccinations etc) is that we are living to be much older than we used to. I must point out that even with all of our advanced medical technology, we still haven’t managed to extend our lives, with most of our faculties (including sexual vigor!) still intact, as long as the Abkhasians or other long-living peoples (110-130 yrs) managed to do without any of our medical intervention.
This book (Abkhasians The Long-Living People of the Caucasus), by Sula Benet, who was born in Warsaw, Poland and later got her PhD at Columbia, is a very comprehensive anthropological study of the Abkhasians culture. I’ve been curious about centenarians ever since I wrote my first paper in Culinary School years ago. Diet, culture and community are obviously all factors in the Abkhasian’s long life, the altitude, amount of exercise and harsh conditions may also play a role. The Abkhasian’s diet fits into what Dr. Weston A. Price found with traditional cultures, although it is interesting to find that they prefer to eat salad for breakfast. Perhaps this is a way to provide enzymes. They also love to drink their matzoni (like yogurt). In line with the GAPS diet or even with a more paleo type diet, the Abkhasians also used nuts quite extensively in their meals, their carbohydrates were mostly from chestnuts, lima beans or cornmeal (which would have been a later addition). They didn’t eat refined flour, oils or sugar. (Image of Abkhasian woman harvesting tea from Sula Benet’s book)
Milk was a very sacred substance for them, and milk-siblings were children who nursed from the same woman. In fact the milk-bond was as powerful as the blood-bond. The Abkhasian society was carefully set up to minimize fighting and to promote community and support within families and tribes. Perhaps our modern world could learn a lot from the way they raise their children, with the whole family supporting and encouraging them and without punishment.
The following are some of my favorite sections from Sula Benet’s book, although there are some really interesting passages that include legends and kinship rituals that I can’t include here. A dry but interesting read.
Abkhasians The Long-Living People of the Caucasus by Sula Benet 1974
Abkhasian Diet:
The Abkhasia diet does not seem to change significantly with an increase in wealth. The daily consumption of protein is an estimated seventy-three grams per person; fat, about 476 grams; and carbohydrates, about 381 grams.
Historically, milk and vegetables make up 70 percent of the Abkhasian diet.
Refined sugar is not a part of the diet. Before retiring, people who wish to have something sweet may take a glass of water with honey. During the autumn harvest, grapes are pressed for their juice, and cornmeal is added to it. The mixture is boiled for a few minutes, allowed to cool, and eaten as a pudding. Or a string of nuts may be dipped into it and dried for dessert. Fruits are dried for the winter as are chestnuts. These are cooked in milk or water, or they may be roasted and accompanied by wine.
Matzoni (Cultured milk):
Abkhasians, young and old, drink one or two glasses of matzoni (Caspian Sea Yogurt) a day. This variety of fermented milk has been used among Caucasian people for many centuries and probably originated in this part of the world. Matzoni is made from the milk of various animals, such as cows, goats and sheep. It has nutritional and physiological value similar to other cultured milks.
Matzoni has low curd tension, which means the curd breaks up into extremely small particles which facilitates its digestion. The fermentation is usually started through the use of matzoni grains, which in appearance resemble small, spongy grains of rice. These masses consist of milk constituents and microorganisms in particular, Bacillus caucasicum and Streptococcus A.
Matzoni can also be produced by adding a few spoonfuls of the previous batch to fresh milk, either skimmed or whole. Fresh cottage cheese without preservatives will work too.
In appearance and taste, matzoni is very much like buttermilk. It has a high food value, and according to Soviet physicians, therapeutic properties as well, especially in the case of intestinal disorders.
Wild pears are cooked into a thick syrup, with no additives, until it resembles jam. This syrup is then used like honey in cooking. Pear jam is also added to hot water and given to sick people to induce sweating which they believe is curative.
Vegetables are served cooked or raw, but are most commonly pickled. A favorite dish eaten almost every day is baby lima beans, cooked slowly for hours, mashed and flavored with a sauce of onions, green peppers, coriander, garlic and pomegranate juice. For memorial rituals lima beans are cooked with crushed walnuts.
Nuts are used in large quantities, grated or crushed for cooking, or eaten whole. Almonds, pecans, walnuts, beech nuts and hazelnuts are cultivated along the coast and in the foothills. Chestnut trees grow wild and profusely, as do many other small wild nut trees. The local population collects large supplies of chestnuts for the winter. They are stored in a special place in the household where they can dry well, and then are used through the winter as needed. A particularly tasty dish, made of chestnuts, is a great favorite of the people. The chestnuts are shelled and then cooked for a long time until they resemble a thick mash. After that assorted nuts such as almonds, pecans, beechnuts, or hazelnuts are added to the mash. The mixture is then served directly upon a wooden table top. A small dent is pressed into each serving of chestnut mash and a small amount of nut oil is poured into the depression.
Toward the end of World War II, nuts were exported from the Caucasus and the people did not have enough for their own needs. Most of Abkhasian food in one way or another is flavored with nuts, never butter. They also serve nuts made in a special way along with vodka, as we would serve hors d’oeuvres.
Abkhasians eat many plants which grow wild in their region, such as the barberry (Barberis vulgaris). This they combine with damson plums and tomatoes for a delicious sauce.
Large quantities of garlic, both cooked and raw, are consumed daily, because Abkhasians like the taste and believe it has medicinal properties.
When meat is boiled, the stock is discarded, since the elders consider it harmful to the constitution. Meat is roasted in open fires on spits and skewers–either wooden or metal. Pomegranate juice is used for basting, enhancing the aroma and adding a reddish color. Though fish abound in the rivers and Black Sea, the people rarely eat them.
In general, foods are cooked without salt or spices, except for adzhika, a hot sauce made of red pepper, salt, dill, garlic, coriander, onions, nuts, damson plums, tomato and beet greens. This mixture is carefully ground on a flat surface with a round stone. The product is aromatic and bitter.
The Abkhasians usually begin breakfast with a salad of green vegetables freshly picked from the garden. During the spring, it always consists of watercress, green onion, and radishes. In summer and winter, tomatoes and cucumbers are most popular, while winter salad consists of pickled cucumber and tomatoes, radishes, cabbage, and onions. Dill and coriander may be added but no dressings are used. The salad is followed by a glass of matzoni. At all three meals the people eat their “beloved abista” (cornmeal mash), always freshly cooked and served warm with pieces of homemade goat cheese tucked into it.
Abkhasians never eat or drink until they are stuffed, for such excessiveness is considered very unbecoming. From childhood on, one learns that in eating, as in all other aspects of Abkhasian life, moderation is valued above all other virtues.
Soviet medical authorities who have examined the Abkhasians and their diet feel it may well add years to their lives. Metchnikoff, the well-known Russian biologist, has suggested that the matzoni and pickled vegetables, and probably the wine, counteract toxic effects of the accumulated products of metabolism in the body and indirectly prevent the development of arteriosclerosis. They also have remarkable hearing. (p23-26)
Milk Siblings (Atalyk):
The term atalyk is used in ethnographic literature to describe a custom once practised in the Caucasus. A boy or girl, shortly after birth, was usually given by a family of greater and social standing to one of a lesser position. However, families of equal standing could do so as well.
The child and his milk siblings (that is the children who were nursed by the same woman) were taught the same customs, skills, and manners, so that an Abkhasian peasant knew as much as a prince.
The link established between two families, one of which received the child of another, was considered sacred and even stronger than the bond of blood. Inter-marriage between the two families, their relatives, and any people of the same surname was immediately forbidden.
When the child came of age, his return home to his natural parents was celebrated by a great feast. His duty to his milk siblings and family continued for life. He protected them from any danger, and came to their assistance in time of need. In fact, all blood and ritual relationships involve lifetime obligations, and ritual kinship is not established lightly. By contrast, merely a sexual relationship, can be dissolved.
This system of milk-siblings served to cement ties between different families, to reduce the distance between social classes, to ensure uniformity of culture, and to make peace between feuding families. In the past, when a family was engaged in a feud and feared retaliation, they would sometimes kidnap a child and declare that they were going to raise it, thus automatically ending the hostilities. The parents of the child could not reclaim it and continue the feud, since the child in all probability had already been nursed, and milk is considered a sacred substance. (p57-58)
Abkhasians are known to perform the ritual with wild animals which have been annoying their homes and livestock in order to gain the goodwill of the animal. I was told that in the community of Khlou, in the region of Khodor, a wolf often attacked the cows and lambs of a shepherd in the village. In desperation, the shepherd when to search for his enemy. It turned out to be a she-wolf with a litter of cubs. He killed the she-wolf but took the little ones to his house, and when they grew up he let them go free, hoping that as their milk-father, he would be immune to wolves and that they could not possibly harm him.
It is said that the shepherd even performed the ritual, his wife sitting on a chair and permitting the cubs to touch her breasts, giving them the status of sons. Since then, the story goes, the wolves never touched his cattle and the shepherd never killed wolves. Mindful of his forest family, he always left some food in the forest for them.
The theme to milk relatives appears frequently in Abkhasian folklore. People felt that it was quite possible to make anyone a milk relative, from a wolf to a god. -p61
Childrearing:
A parent expresses disapproval by withholding praise, which is otherwise very generously dispensed. The Abkhasian concept of discipline, considered necessary and good for children, in not intertwined with the concept of punishment. Abkhasians feel taht physical punishment induces disrespect. This may be the reason for so little resentment between the generations: the Abkhasian method of discipline does not allow for the development and expression of even the mildest forms of sadistic impulse. Also, with no threat of punishment there is less attempt on the part of the child to see how far he can go. -p69
Sexuality:
The Abkhasians expect to live long and healthy lives. They feel that self-discipline is necessary to conserve their energies instead of grasping what sweetness is available to them at the moment.
The general opinion among Abkhasians is that regular sexual relations should start late in life, because abstinence will prolong sexual potency and promote wellbeing. Postponement of satisfaction is not deemed frustrating but, rather, a hopeful expectation of future enjoyment. A continuation of sex life into old age is considered as natural as maintaining a healthy appetite or sound sleep. Abkhasians do not think that there is any reason why increased years should stip them of so human a function.
Among the aged, there are no bachelors or spinsters. Celibacy is regarded to a certain extent, as abnormal, antisocial, and contrary to human nature. In one study, only one elderly spinster in the village of Shroma could be found. Very often, the old people give their good family life and late marriages as some fo the reasons for their longevity. Many of the Abkhasian aged got married between the ages of forty and fifty, which was considered quite normal in former times, and stayed married for fifty, severnty, or even eighty years. There are quite a number of instance where both husband and wife are still alive, and often the husband is older by twenty to thrity years. At present, to the consternation of the elders, young people tend to marry in their middle twenties, instead of waiting until the more “proper” age of thirty.
Despite the elaborate rules–perhaps, in part, because they are universally accepted–sex in Abkhasia is considered a good and pleasurable thing when it is strictly private. As difficult as it may be for the American mind to grasp, it is also guiltless. It is not repressed or sublimated into work, art, or religious-mystical passion. It is not an evil to be driven from one’s thoughts. It is a pleasure to be regulated for the sake of one’s health–like a good wine. -p86

https://www.helladelicious.com/blog/2011/08/diet-and-culture-of-abkhasian-centenarians/ 

Misao Okawa, Oldest Living Person Until 2015, 117 - sushi, especially mackerel on vinegar-steamed rice.

Misao Okawa, Oldest Living Person Until 2015, 117

In Japan, where there are over 65,000 centenarians, Okawa held the record for world’s oldest person until her death in 2015. She told The Guardian, “You have to learn to relax,” in order to hit those digits, but also get plenty of sleep. Her favorite food was sushi, especially mackerel on vinegar-steamed rice.

https://www.bonappetit.com/story/oldest-person-in-world-food


Monday, 8 May 2017

THE PEANUT PUZZLE

MEDICAL DISPATCH  FEBRUARY 7, 2011 ISSUE


Could the conventional wisdom on children and allergies be wrong?
By Jerome Groopman

Food allergy is likely a problem that we’ve created through our diet and environment.
Food allergy is likely a problem that we’ve created through our diet and environment.
Illustration by RICHARD MCGUIRE

Jill Mindlin prides herself on being a good parent. An attorney who lives on the North Shore of Long Island, she read books about how to raise healthy and happy children and dutifully followed their advice. She bought the car seat with the highest safety rating and covered her son and daughter with sunblock whenever they went outside. With her pediatrician’s approval, she breast-fed her children until they were at least a year old and gave them “no formula whatsoever” and no milk products or peanuts. As the American Academy of Pediatrics recommended in 2000, she introduced solid foods slowly and in small amounts.

In 2002, when her daughter, Maya Konoff, was nine months old, Mindlin took Maya for a checkup, and she got several immunizations. After they came home, Mindlin gave her a little yogurt. Soon, Mindlin told me, “Maya blew up like a tomato, bright red, swelling from head to toe.” She called the office, assuming that her daughter was reacting to the immunizations. The pediatrician told her that it was more likely an allergy of some kind. “Fortunately, there was liquid Benadryl in the house, and I was able to get Maya to take some,” Mindlin said. The reaction slowly subsided.

Several days later, Mindlin took Maya to see a pediatric allergist at a hospital on Long Island, and he told her it was unlikely that her daughter had a dairy allergy, since she had been breast-fed and was on a restricted diet. But Mindlin asked that Maya be examined, and the allergist placed a small amount of milk protein under the baby’s skin. Within minutes, she broke out in hives. As it turned out, Maya was also allergic to eggs, peanuts, tree nuts, and sesame seeds.

Despite her mother’s vigilance, Maya has had other frightening reactions. On a family outing to the Long Island Children’s Museum a few months later, after eating something labelled “vegetarian cheese,” Maya struggled to breathe and then lost consciousness. On vacation in South Carolina in 2003, Maya wanted a hot dog. “We asked the waiter to be sure that there were no dairy products in the food,” Mindlin recalled. “He came back to the table and said that the package said a hundred per cent beef.” But a few minutes after eating the hot dog Maya began vomiting and swelling. Mindlin later learned that the hot dog contained a milk protein. This time, the doctor in the E.R. gave Maya an epinephrine injection. Epinephrine, another term for adrenaline, can rapidly shut off a severe allergic reaction, and Mindlin now makes sure there are syringes of it in each of her handbags and in Maya’s knapsack.

Dr. Hugh Sampson, the director of the Jaffe Food Allergy Institute at Mount Sinai Medical Center in New York and an international expert on food allergy, is Maya’s doctor. He is a tall sixty-year-old with an athletic build and a full head of graying hair. Sampson and Dr. Scott Sicherer, a pediatric allergist who is also at Mount Sinai, have conducted extensive studies throughout the United States that show that the rate of allergy is rising sharply. Sampson estimates that three to five per cent of the population is allergic to milk, eggs, peanuts, tree nuts, or seafood. In the past decade, allergies to peanuts have doubled. Other researchers have found the same phenomenon in Great Britain. “This increase in the incidence of food allergy is real,” Sampson said when we spoke recently. He cannot say what is causing the increase, but he now thinks the conventional approach to preventing food allergies is misconceived. For most of his career, he believed, like most allergists, that children are far less likely to become allergic to problematic foods if they are not exposed to them as infants. But now Sampson and other specialists believe that early exposure may actually help prevent food allergies.

Sampson recalls that, in 1980, when he started researching the subject, as a fellow in immunology at Duke University, “food allergy was not a field that anybody wanted to get into.” Many doctors said that patients who claimed that food allergies were causing stomach aches and rashes were often just manifesting psychosomatic symptoms. “I approached the subject with the assumption that I would prove it didn’t exist,” Sampson said.

In one early test, he gave a girl in the first grade a bit of egg camouflaged in applesauce. To Sampson’s astonishment, she started wheezing and projectile vomiting. Five years later, he found that his one-year-old daughter was allergic to eggs. As Sampson got deeper into his work, he was struck by how little was known about the condition. No one knew why some children react to a food protein when it is placed on their skin but not when they eat it, or why others have antibodies in their blood that predict allergic reactions they don’t end up having.

Sampson watched as the incidence of food allergies rose alarmingly in the West while cases remained rare in Africa and Asia. He and other researchers began to investigate whether the problem could be prevented if Western mothers continued breast-feeding as long as possible. This would keep their babies away from potentially allergenic foods until their immune systems had developed sufficiently. Laboratory studies reinforced the theory. Sampson’s research group and others found that mice that had never been exposed to a particular food protein couldn’t mount an allergic reaction to it. This suggested that isolating young children from even minor exposure to potentially allergic foods would be beneficial.

In 1989, Dr. Robert Zeiger, a pediatric allergist and immunologist at Kaiser Permanente Medical Center in San Diego, published related results from one of the only controlled research studies on the subject. In the Zeiger study, which appeared in The Journal of Allergy and Clinical Immunology, mothers prone to allergy were randomly assigned a restricted diet. They avoided cow’s milk, eggs, and peanuts during the last trimester of pregnancy and during breast-feeding; their infants were given the supplement Nutramigen, derived from casein, and kept off all solid foods for six months; cow’s milk, corn, soy, citrus, and wheat were prohibited for twelve months, and egg, peanut, and fish for twenty-four months. After one year, the infants on the restricted diet had significantly fewer allergies than those in the control group. “Reduced exposure of infants to allergenic foods appeared to reduce food sensitization and allergy primarily during the first year of life,” Zeiger wrote.

A few experts believed that Zeiger’s research had not yielded results from which one could draw major conclusions. But Sampson was influenced by the article, and most of the other leading thinkers in the field agreed with the findings. “We know that the human immune system is immature for the first year or so. So I was thinking initially that, as long as we don’t expose babies to a food, they can’t make an immune response,” Sampson said, “and if we can wait until their immune system matures after a few years they could do better when later exposed to the food.”

In 1998, the Department of Health in the United Kingdom issued guidelines for doctors and families codifying these recommendations. In 2000, the American Academy of Pediatrics did the same.

The proteins within eggs, milk, peanuts, tree nuts, fish, shellfish, wheat, and soy that trigger allergic reactions don’t readily decompose when exposed to heat in certain types of cooking or to the acid in our stomachs. Within the gastrointestinal tract, the immune system battles pathogens while it ignores harmless food proteins and allows nonthreatening bacteria to reproduce. Proteins that are easily broken down by heat or digestion, such as many of those found in fruits, generally pass by. Proteins that resist breakdown are more likely to stimulate an allergic reaction.

People with the worst food allergies usually have very high levels of an antibody called immunoglobulin E (IgE). When someone like Maya drinks milk, the IgE grabs hold of specific proteins that trigger the body’s release of potent molecules like histamine and cytokines. The immune system overreacts to fight the protein that most people’s bodies ignore. When Maya “blew up like a tomato” and stopped breathing, it was because these molecules created so much swelling and inflammation that her throat closed up. For reasons that are still not completely understood, some people manifest their allergic reactions with nothing more than an outbreak of eczema. While there is a genetic predisposition to food allergies, no one has identified the specific genes, and there is no biological explanation for their existence.

“From an evolutionary-biology point of view, food allergy makes no sense at all,” Dr. Scott Sicherer, Sampson’s colleague at Mount Sinai, said. Hunters and gatherers who had potentially fatal reactions to tree nuts, peanuts, seeds, and fish would be at a distinct evolutionary disadvantage and were less likely to pass on their DNA to progeny. “It seems pretty clear that food allergy is a condition that resulted from the environment we created,” Sicherer said.

One explanation for the rise in food allergies is called the “hygiene hypothesis.” The natural environment exposes us to microbes that help teach our immune system to differentiate between dangerous pathogens and nonthreatening nutrients. When we shield children from dirt in the playground and from sick kids in preschool, we may limit their infections while also reducing their exposure to healthy microbes. This could make them susceptible to food allergies. Studies of mice raised in a germ-free environment show that they have abnormal immune systems and are more prone to allergic reactions. It is possible that we are doing the same thing to ourselves.

Researchers have also proposed several theories based on observations of geography and diet. Vitamin D is believed to reduce the development of allergies, and sunshine promotes vitamin-D production. Doctors in cold parts of the United States write three or four times as many prescriptions for epinephrine to treat food allergies as do doctors in warm locales. Dietary changes might also play a role. Eating more animal fat can increase the presence of a chemical, prostaglandin, that contributes to the body’s inflammatory responses. And as people also eat fewer fresh fruits and vegetables they fail to take in substances, such as beta-carotene, that limit inflammation in tissues.

One of the few pediatric allergists who questioned the guidelines written in 1998 and 2000 was Dr. Gideon Lack, at St. Mary’s Hospital in London. Lack studied philosophy and psychology before medicine, and his background is evident in his approach to science. “If eating eggs or eating peanuts in an allergic sufferer causes a reaction, then clearly the way to prevent a reaction from occurring is by not eating egg or peanut,” he said. “That makes sense. But that’s different from saying that clearly the way to not become allergic in the first place is not to eat egg or peanut.”

Lack published letters in The Lancet and the British Medical Journal that pointed out the absence of compelling evidence used to support the expert guidelines. His skepticism was not well received. “It was very hard to get any grant support to study my ideas,” he said.

In 2003, Lack gave a lecture in Israel about the apparent rise of peanut allergies in the United Kingdom. “It was a large lecture hall in Tel Aviv, filled with pediatricians and allergists. And I asked them, ‘How many of you have seen a case of peanut allergy in the past year?’ Something like three hands shot up.” Lack told me that if he had asked that question in the United Kingdom, ninety to ninety-five per cent would have raised their hands.

Cartoon
“Mr. Butler, your ten-o’clock is here.”
ShareTweetBuy a cartoon
Working with researchers in Israel, Lack surveyed more than five thousand children in Jewish schools in North London and more than five thousand schoolchildren in an ethnically and economically similar region of Tel Aviv. The team obtained detailed information about the families’ consumption of foods like peanuts, sesame, and tree nuts. They also catalogued other allergic diseases, such as asthma, eczema, and hay fever. The risk for peanut allergy among Jewish children in the London area was nearly eleven times higher than among those in Tel Aviv. Tree-nut allergy was fourteen times higher, and sesame five times higher in the United Kingdom. The relative risk for milk and egg allergy was about two to three times higher.

Lack’s study does not offer any proof about the cause of the variance in allergies between Jewish children in London and in Tel Aviv, but he believes the striking discrepancy may be due to a difference in diet between Israel and England. “The joke in Israel is that the first three words a child says are abba, meaning ‘father,’ ima, meaning ‘mother,’ and Bamba,” Lack said. Bamba is a peanut concoction that looks like a Cheez Doodle, and it is a staple of infants’ diets in Israel.

Lack did part of his training in pediatric allergy at the National Jewish Medical and Research Center in Denver, where he discovered that mice could develop allergies to a particular egg protein that was first rubbed on their skin or inhaled before they had ever eaten it. He wondered whether children in the United States and the United Kingdom might become allergic to peanuts through a similar mechanism. In a study published in The New England Journal of Medicine in 2003, he reported that children with eczema had often been previously exposed to an ointment containing peanut oil and were later found to be allergic to peanuts. He also determined that there was no correlation between women who had eaten peanuts while pregnant and the development of peanut allergies in their children. His study challenged the idea that restricting a mother’s diet would prevent peanut allergy, and highlighted how children can inadvertently be exposed to food proteins.

In 2006, Lack received support from the National Institutes of Health as well as from two charitable organizations, the Food Allergy Initiative and the Food Allergy and Anaphylaxis Network. He is now more than halfway through the leap study—Learning Early About Peanut Allergy. Six hundred and forty babies have been enrolled in the trial. The children are randomly selected either to eat peanut products or to avoid them entirely. The study will compare the rates of peanut allergy between the two groups. Lack is also conducting a study funded by the Food Standards Agency and the Medical Research Council, in the United Kingdom, about when to wean children from breast-feeding and how a baby’s consumption of allergenic foods affects her later development of allergies. As part of that work, he is examining thirteen hundred babies in the United Kingdom.

Lack believes that a child becomes tolerant to a variety of food proteins through exposure in the first six months of life. In developing countries, he notes, children often consume solids, initially chewed by their parents, at two or three months. “Years ago, nobody had blenders or food mixers, and today in developing countries people still don’t. The easiest way to get solid foods into a baby’s mouth is to chew it up, so it’s moist and coated with saliva, and then spit it into the baby’s mouth.”

A paper published in Maternal and Child Nutrition in January, 2010, reported that some two-thirds of students at a university in China were given premasticated food as infants. Only about fourteen per cent of American infants receive solid foods in this way. Saliva is a rich source of enzymes that can help break down solid foods and of antibodies that might coat food proteins in a way that makes them less allergenic to infants.

Lack’s research has gradually gained influence with leading allergists, including Hugh Sampson. By 2006, Sampson realized that his recommendations about food avoidance did not conform to what he termed “the real world.” Doing nothing more than inhaling or touching an allergen could prompt a reaction in some children. “You can’t avoid food proteins,” Sampson said. “So when we put out these recommendations we allowed the infants to get intermittent and low-dose exposure, especially on the skin, which actually may have made them even more sensitive.”

Sampson believes that some eighty per cent of infants who are allergic to eggs or milk will outgrow the allergy by their teen-age years, and that preventing them from being fed products with these foods may prolong the time that takes. “I spent most of my career telling mothers to avoid these types of foods for their babies,” he told me. “Now we’re testing to see if we should advise mothers to give the foods to them.”

In January, 2008, the American Academy of Pediatrics released a clinical report by Mount Sinai’s Dr. Sicherer and other researchers that overturned the expert advice of the past decade: “Current evidence does not support a major role for maternal dietary restrictions during pregnancy or lactation. . . . There is also little evidence that delaying the timing of the introduction of complementary foods beyond four to six months of age prevents the occurrence of [allergies].” Dr. Frank Greer, a specialist in newborn nutrition at the University of Wisconsin School of Medicine and Public Health and an author of the clinical report, told me, “There is so much out there about how to feed infants, when to begin rice cereal, how to phase in yellow vegetables and then green vegetables, that has no basis in scientific evidence. It’s not surprising that recommendations were made which were based on so little data.”

Dr. Susan Baker, a professor of pediatrics at the State University of New York at Buffalo and an expert on nutrition for children, chaired the committee overseen by the A.A.P. that released the recommendations in 2000. She told me that safety concerns drove the experts to recommend restricting exposure of infants to potentially allergenic foods, particularly cow’s milk. “At the time, there was a proliferation of infant formulas on the market. Babies not only have cow’s milk allergy with eczema, but some who are intolerant of milk also develop bloody diarrhea. The real concern was that the formulas might do harm. That sort of propelled us.” The committee, she said, moved from milk products to restricting other allergenic foods, like peanuts and fish. “We in medicine are making a lot of decisions and recommendations based on not a lot of solid evidence. So you toe a fine line. You want to try to get pediatricians something that is as good as it can be to help guide their practice and their thinking. Did we overreach with peanuts and other foods? Probably. Could it have been better? Absolutely.”

The 2000 recommendations have now been overturned, but Gideon Lack is disturbed by what families now face. “Basically, we are all in limbo,” he said. Sicherer told me, “This is a tricky area. The A.A.P. has backed away from making recommendations, since the evidence is weak. I try to emphasize with my patients not to feel guilty that they did or did not do something that would have resulted in their child having a food allergy. Even the experts are not certain what to advise.”

People with food allergies live under a constant threat, in a society that is still poorly informed about the condition. For people with peanut and tree-nut allergies, incidents in restaurants account for nearly a quarter of unintentional exposures and about half of all fatal reactions.

In 2007, Sicherer published the results of a survey of a hundred managers, servers, and chefs in establishments ranging from continental restaurants to bakeries and delis. Focussing on New York City and Long Island, Sicherer found that about a quarter of managers and workers believed that consuming a small amount of the allergen would be safe; thirty-five per cent believed that frying would destroy it; and a quarter thought it was safe to remove an allergen from a finished meal, like taking walnuts out of a salad. Nearly three-quarters of food workers believed that they knew how to “guarantee” a safe meal. Most states do not require that food providers attend educational programs, and there are no national requirements.

Sampson, acutely aware of the risks facing food-allergy sufferers, is now trying to work out a way to help desensitize people. To do this, he is relying on the idea behind the hygiene hypothesis and some of Lack’s investigations: that exposure in small doses, in controlled circumstances, can build tolerance. He is trying to identify how the IgE antibody attaches to different proteins, and he uses this knowledge to have foods cooked in a way that would make the proteins less allergenic. Researchers at Mount Sinai observed, for example, that baking caused milk proteins to change shape in a way that could be less provocative to the immune system. An allergic person might be able to eat the altered proteins and become tolerant of them in all their forms. Sampson and other researchers have also configured an experimental vaccine that contains fragments of peanut protein that might “reëducate” the immune system of allergic people. Safety studies of the experimental vaccine are under way at the Jaffe Institute.

In 2008, when Maya Konoff was seven, her mother enrolled her in a research study being conducted by Dr. Sampson at the Jaffe Food Allergy Institute, funded by the N.I.H. She was given allergens in an altered form, and if she achieved tolerance she would be given foods that contained the allergen in its more natural state.

The treatment rooms at the institute are painted in soft tones and the hallways are decorated with large photographs of fruits. The institute has a spotless stainless-steel kitchen; all the refrigerators and cabinets are kept locked. Diego Baraona, the chef, prepares the foods. When I visited, he showed me a batch of small muffins he had baked, with applesauce and milk, and cups of rice pudding tightly sealed in plastic. With a nurse and Jill Mindlin at Maya’s side, the child was given a muffin. Maya tentatively took a bite, waited, and seemed to have no reaction. In short order, she ate the rest of the muffin. “It was very exciting for our family,” Mindlin recalled, “because it meant that she was one of those kids whose bodies didn’t recognize the milk protein when it was broken down in baking, so now she had potential to eat baked foods.”

The next step was to try a taste of pizza. Maya took her first bite, waited, smiled, and then took another two bites. “I knew right then that things were not going well, even though Maya had not exhibited any physical symptoms,” Mindlin said. “She had been so giddy, riding off the high of eating the muffin, happy and chattering, and then all of a sudden there was this pall that came over her.” Maya soon broke out in hives and began vomiting. Sampson gave her an epinephrine injection. As the drug took effect, the anaphylactic reaction was arrested.

According to the protocol, Maya was supposed to come back in six months. Dr. Sampson counselled that in the meantime she should eat baked foods that included milk. When she returned, an intravenous line was inserted and an epinephrine inject pen was placed at the bedside before Maya was offered a slice of the same pizza. “It was nothing less than miraculous,” her mother told me. “She ate the entire slice of pizza.” Maya was observed for several hours and then given a bowl of rice pudding. The doctors told Mindlin to expect a reaction. “But instead she ate the whole bowl of rice pudding and was fine. She jumped two levels, just by eating muffins every day,” Mindlin said.

Maya returned to Mount Sinai the next day for a glass of milk. “That didn’t go quite as well,” Mindlin said. As Maya finished drinking, her nose began to run and she vomited. The allergic reaction was mild enough to be treated with Benadryl. When I spoke to Mindlin in December, she told me that Maya can now eat macaroni and cheese but that she is still unable to drink milk. “Even if she never progresses past this, I have no regrets about being in the study, because now she can go to a birthday party and have a slice of pizza. It’s huge.” ♦


Jerome Groopman, a staff writer since 1998, writes primarily about medicine and biology. More

http://www.newyorker.com/magazine/2011/02/07/the-peanut-puzzle

Monday, 10 October 2016

Seafood continues to be deemed the most hazardous food in analyses of food-borne disease outbreaks.

MaryF Maryland 16 hours ago

Why replace one problematic food with another? In addition to mercury, dioxins, PCBs and other accumulated toxins, fish are often infested with parasites. Seafood continues to be deemed the most hazardous food in analyses of food-borne disease outbreaks.


Colenso Cairns 16 hours ago
'Nutrient content varies depending on the type of fish: Shellfish is especially high in selenium, and saltwater fish is high in iodine, Ms. McDaniel said.'

Look, I know this is not a term paper let alone an article in Nature, but can't the NYT make even the slightest effort to fact check the basic science and get it right?

Shellfish are not fish, but rather marine, briny or freshwater dwelling animals that are completely different to fish.

Is a platypus a fish because it dwells in streams? Is a whale a fish because it lives in oceans? Is a walrus a fish? How about a beaver and an otter?

Just as termites are not white ants, shellfish are not fish. No wonder most American adults are so clueless about basic science, deny global warming etc etc. It all starts with sloppy, lazy and inaccurate reporting like this.


Source: Comments section in article below:
http://well.blogs.nytimes.com/2016/10/07/why-is-fish-good-for-you-because-it-replaces-meat/?smid=fb-nytimes&smtyp=cur&_r=0