First ever study finds - Fungus plays a key role in development of Crohn's

1. Crohn’s disease is an inflammatory bowel disorder that results in inflammation of the digestive tract.

2. Abdominal pain, severe diarrhea and fatigue, are among the most common forms of inflammatory bowel disorder.

3. Currently, there is no remedy for the disease.

4. Researchers at Case Western Reserve University have discovered a fungus that works with two types of bacteria to cause symptoms of Crohn’s. This is the first study to find a fungus that plays a role in the development of the disease. The hope is that the identification leads to new ways of treating Crohn’s.

5. E. Coli & Serratia Marcescens

Published in the journal mBio, the study reviewed the fecal samples of 20 people with Crohn’s disease, as well as samples of 28 of their family members who don’t suffer from the disease, and 21 people without the disease whose family members also did not have it.
The researchers discovered that the people with Crohn’s had two bacteria present in their feces — E. coli and Serratia marcescens — that move “in lock step” with the fungus Candida tropicalis. Together, the three produce a biofilm that triggers inflammation linked to Crohn’s disease.

6. The researchers also noted that the bacteria and fungus came in much bigger concentrations in samples from patients as opposed to their family members. Overall, bacterial and fungal makeup from those without Crohn’s or family with it was very different.

7. “Among hundreds of bacterial and fungal species inhabiting the intestines, it is telling that the three we identified were so highly correlated in Crohn’s patients,” explained Ghannoum. “Furthermore, we found strong similarities in what may be called the ‘gut profiles’ of the Crohn’s-affected families, which were strikingly different from the Crohn’s-free families. We have to be careful, though, and not solely attribute Crohn’s disease to the bacterial and fungal makeups of our intestines. For example, we know that family members also share diet and environment to significant degrees. Further research is needed to be even more specific in identifying precipitators and contributors of Crohn’s.”

http://wisemindhealthybody.com/collective-evolution/fungus-found-inside-human-identified-for-the-first-time-as-key-contributor-in-crohns-disease/?cpt=dax